Analytical method development and validation plays important role in the discovery, development and manufacture of pharmaceuticals. A simple, rapid and reproducibe UV- spectrophotometric method for the quantitative determination of caffeine in tablet formulation was developed and validated in the present work. The parameters lineartiy, specificity, precision, accuracy, robustness and ruggedness was studied according to ICH guidelines. The wavelength 270nm was selected for the estimation of drug using distilled water as a solvent. The drug obeyed Beer-lamber’ts law over the concentration range 10-50Hg/ml. The accuracy of the method was assessed by recovery studies and was found between 99.46- 100.67%. The method was successfully applied for routine analysis of this drug in formulations.