Antidepressant Activity of Dichloromethane Extract of Valeriana jatamansi Roots

International Journal of Novel Trends in Pharmaceutical Sciences,2011,1,1,33-35.
Published:October 2011
Type:Research Article
Authors:
Author(s) affiliations:

Ashwani Kumar*

Akal College of Pharmacy & Technical Education, Mastuana Sahib, Sangrur, Punjab-148001, India

Abstract:

The present study was designed to evaluate the antidepressant activity of Valeriana jatamansi (Fam. Valerianaceae) roots. The dichloromethane extract was subjected to antidepressant activity evaluation on lacca mice using forced swimming test. The standard and test extract were administered per oral route. Dichloromethane extract of the roots exhibited significant dose dependent antidepressant activity at 400 mg/kg, comparable to that of standard imipramine (12.5 mg/kg). 

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Analgesic Antidepressant Activity of Dichloromethane Extract of Valeriana jatamansi Roots